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Updated: May 15, 2026

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease
Published on: July 19, 2024
[Relationship gene polymorphism adipor1 with cardiovascular risk in patients with nonalcoholic fatty liver disease]
1GI "L.T. Malaya Therapy Institute of the NAMS Ukraine", Kharkov.
Abstract:
The aim of the research was to study the link between the polymorphic gene ADIPOR1 and the development of cardiovascular risk in patients with non-alcoholic fatty liver disease (NAFLD). It was found that the carriers of the G allele ADIPOR1 rs 1342387, compared with the carriers of the A allele have a potentially higher degree of cardiovascular risk. NAFLD carriers of the G genotype ADIPOR1 observed proatherogenic lipid profile and a significant increase in the thickness of the intima-media. The results confirm the modulation of genetic factors in the implementation of cardiovascular risk in patients with NAFLD.
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