[OPTIMIZATION OF DIAGNOSIS OF PULMONARY HYPERTENSION SYNDROME IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE...

Objective - to develop a new additional method for assessing the level of pulmonary artery pressure in patients with chronic obstructive lung obstruction (COPD) in combination with ischemic heart disease (IHD), which will improve the quality of early diagnosis of pulmonary hypertension syndrome in this category of patients. The study included 104 male patients diagnosed with COPD in combination with IHD. All patients were subjected to a comprehensive clinical examination, examination of the function of external respiration, ultra sound examination of the structural and functional state of the heart and blood vessels, determination of blood levels of factors of the systemic inflammatory response. Based on the data obtained from the study, it was assumed that the values of the smoking index (IC), the forced expiratory volumein 1 s (FEV1), the average volumetric rate of the forced vital capacity of the lungs (COC25-75), the content of the C-reactive protein in the plasma blood (CRP) can be prognostic markers for the formation of pulmonary hypertension in the comorbidity of COPD with IHD and a use ful model for determining mean pulmonary artery pressure. Calculation of mean pulmonary artery pressure in patients with COPD with and IHD contributes to anincrease in the effectivenes sofearly diagnosis of pulmonary hypertension syndrome, which inturn will help optimize the assessment of the prognosis and therapy of this contingent of patients.