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Brain Slice Stimulation Using a Microfluidic Network and Standard Perfusion Chamber
Published on: October 1, 2007
Advances in microfluidics-based experimental methods for neuroscience research
Jae Woo Park1, Hyung Joon Kim, Myeong Woo Kang
1Division of WCU (World Class University) Multiscale Mechanical Design, School of Mechanical and Aerospace Engineering, Seoul National University, Seoul, Korea.
Lab on a Chip
|January 12, 2013
Summary
Microfluidics and biological micro-electro-mechanical systems (BioMEMS) offer precise control for neuroscience research. This review highlights recent BioMEMS advancements in disease models, electrophysiology, and neural stem cell studies.
Area of Science:
- Neuroscience
- BioMEMS
- Microfluidics
Background:
- Microfluidics enables precise spatial and temporal control of the cellular microenvironment in neuroscience.
- Biological micro-electro-mechanical systems (BioMEMS) have seen rapid development for neuroscience research.
Purpose of the Study:
- To review recent advances in BioMEMS for neuroscience applications.
- To summarize progress in BioMEMS components, design, in vitro disease models, electrophysiology, and neural stem cell research.
Main Methods:
- Literature review of recent advancements in BioMEMS for neuroscience.
- Analysis of applications in disease modeling, electrophysiology, and stem cell research.
Main Results:
- Significant progress in BioMEMS components and design for neuroscience.
- Emerging applications in in vitro disease models, electrophysiology, and neural stem cell research.
Conclusions:
- BioMEMS and microfluidics are crucial tools for current and future neuroscience research.
- These technologies facilitate both fundamental and applied neuroscience investigations.
