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Electrophysiology on Isolated Brainstem-spinal Cord Preparations from Newborn Rodents Allows Neural Respiratory Network Output Recording
Published on: November 19, 2015
Control of breathing in invertebrate model systems
1Division of Pulmonary and Critical Care, Department of Medicine, Penn State University, Hershey, Pennsylvania, USA. sthomson@ucsd.edu
Comprehensive Physiology
|June 1, 2013
Summary
Invertebrates use diverse respiratory structures and control mechanisms for oxygen uptake. Studying these animals reveals fundamental principles of breathing control conserved across species.
Area of Science:
- Zoology
- Comparative Physiology
- Neurobiology
Background:
- Invertebrates exhibit diverse respiratory structures (lungs, gills, tracheal systems) for oxygen extraction.
- Like vertebrates, invertebrates possess complex regulatory mechanisms for breathing activity.
Purpose of the Study:
- To describe known breathing control mechanisms in invertebrate model systems.
- To explore respiratory rhythm generation, chemosensory modulation, and breathing plasticity.
Main Methods:
- Review of established invertebrate models for respiratory control research.
- Examination of behavioral and neuronal adaptability in breathing control.
Main Results:
- Invertebrate models elucidate fundamental principles of respiratory rhythm generation.
- Chemosensory pathways and plasticity significantly modulate invertebrate breathing.
- Neuronal adaptability in breathing control is extensively documented.
Conclusions:
- Invertebrate models provide insights into conserved neuronal mechanisms of respiratory control.
- Understanding invertebrate breathing control offers a foundation applicable to vertebrates.
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