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Updated: May 10, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
Published on: July 8, 2025
Bilateral paramedian thalamic infarction initially presenting as a convulsive seizure
Jianping Wang1, Xiaojie Fu, Chao Jiang
1Department of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Henan, Zhengzhou 450052, China.
Bilateral paramedian thalamic infarction, a rare condition, can initially present as a convulsive seizure. This case highlights the importance of recognizing this presentation for timely ischemic stroke management.
Area of Science:
- Neurology
- Neuroimaging
- Stroke Medicine
Background:
- Bithalamic infarctions are uncommon neurological events.
- Convulsive seizures as an initial presentation are rarely documented.
- Bilateral paramedian thalamic infarction has not been previously reported in China.
Purpose of the Study:
- To report a case of bilateral paramedian thalamic infarction presenting with convulsive seizure.
- To discuss the potential link between thalamic infarction and seizures.
- To raise awareness among physicians regarding this rare clinical presentation.
Main Methods:
- Case report of a patient with new-onset convulsive seizure.
- Diffusion-weighted imaging (DWI) to identify infarct location and vascular supply.
- Review of existing literature on thalamic infarction and seizures.
Main Results:
- The patient presented with a convulsive seizure.
- Diffusion-weighted imaging confirmed bilateral paramedian thalamic infarction.
- The infarct area was supplied by the artery of Percheron.
Conclusions:
- Convulsive seizure may be an initial symptom of bilateral paramedian thalamic infarction.
- The artery of Percheron is implicated in this specific type of thalamic infarction.
- Prompt recognition is crucial for initiating seizure control and ischemic stroke management.
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