Related Experiment Video
Updated: May 9, 2026

10:45
Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space
Published on: July 24, 2017
An amplitude-to-time conversion technique suitable for multichannel data acquisition and bioimpedance imaging
Jong Cheol Baeg1, Hun Wi, Tong In Oh
1Department of Biomedical Engineering, College of Electronics and Information, Kyung Hee University, Yongin-si, Gyeonggi-do 446-701, Korea.
IEEE Transactions on Biomedical Circuits and Systems
|July 16, 2013
Summary
This study introduces a novel amplitude measurement technique for bioimpedance systems, reducing component count and cost. The method leverages microprocessor timing resolution for efficient sinusoidal signal recording in portable impedance imaging.
Area of Science:
- Electrical Engineering
- Biomedical Engineering
- Signal Processing
Background:
- Traditional amplitude measurement in high channel count systems is component-intensive.
- Existing methods for bioimpedance and impedance imaging are often costly and bulky.
- Portable sinusoidal recording systems require efficient and low-power amplitude measurement.
Purpose of the Study:
- To develop a novel amplitude measurement approach for high channel count portable sinusoidal recording systems.
- To reduce component count, cost, size, and power consumption in bioimpedance measurements.
- To enhance the convenience and efficiency of impedance imaging systems.
Main Methods:
- Exploiting high timing resolution of microprocessors for amplitude measurement.
- Utilizing two high-performance comparators to convert amplitude difference to timing difference.
- Employing a high-speed microprocessor for data capture and a straightforward algorithm for offset removal.
Main Results:
- The developed approach significantly reduces component requirements per channel.
- Three operational modes (fast, normal, high precision) were proposed.
- Mean signal-to-noise ratios of 40, 81, and 112.4 dB were achieved in fast, normal, and high precision modes, respectively.
Conclusions:
- The novel amplitude measurement technique is suitable for high channel count portable sinusoidal recording systems.
- This method offers a cost-effective, size-efficient, and power-saving alternative to traditional approaches.
- The approach demonstrates high signal-to-noise ratios across different operational modes, validating its effectiveness for bioimpedance applications.
Related Concept Videos
Instrumentation Amplifier
An electrocardiography (ECG) machine is an essential piece of medical equipment used to monitor the electrical activity of the heart. It operates by detecting small electrical changes on the skin that result from the depolarization of the heart muscle during each heartbeat. However, these signals are in the microvolt range and can be easily overwhelmed by noise or interference.
To overcome this challenge, an ECG machine utilizes an instrumentation amplifier. This specialized amplifier is...
To overcome this challenge, an ECG machine utilizes an instrumentation amplifier. This specialized amplifier is...
Bode Plots Construction
The Bode plot is an essential tool in control system analysis, mapping the frequency response of a system through a magnitude plot and a phase plot, both against a logarithmic frequency axis. To construct a Bode plot, consider the transfer function H(ω):
Amperometry: Overview
Amperometry is a technique commonly used to measure the concentration of specific analytes in a solution by monitoring the electric current generated during an electrochemical reaction. It involves applying a constant potential between a working electrode and a reference electrode to measure the resulting current, which is proportional to the concentration of the analyte. The Clark oxygen electrode operates based on this principle of amperometry. It consists of a cathode and an anode enclosed...
