Related Experiment Video
Updated: May 6, 2026
09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
3.3K
[Skin cancers infiltrating the skull base].
P Pasche1, M Broome, R T Daniel
1Service d'ORL et de chirurgie cervico-faciale, CHUV, 1011 Lausanne. philippe.pasche@chuv.ch
Revue Medicale Suisse
|November 6, 2013
Summary
Aggressive facial skin cancers, though rare, can invade deep tissues and bone. Advanced treatments offer curative options, but careful patient selection is crucial for therapeutic benefit.
Area of Science:
- Oncology
- Craniofacial Surgery
- Dermatology
Background:
- Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) of the face typically have a good prognosis.
- A subset of these facial skin cancers exhibits aggressive behavior, infiltrating deep soft tissues and bone.
Observation:
- Tumor invasion can follow embryonic fusion lines or facial nerves, potentially reaching craniofacial skeleton and intracranial structures.
- This aggressive behavior may manifest years after initial treatment.
Findings:
- Advances in craniofacial surgery, reconstruction techniques, and conformational radiotherapy enable curative treatments for advanced cases.
- Despite treatment advancements, these tumors present a limited prognosis.
Implications:
- Rigorous patient selection is essential for achieving therapeutic benefit in advanced facial skin cancers.
- Multidisciplinary approaches combining surgery, radiation, and reconstruction are vital for managing these complex cases.
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