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Volumetric R2 * mapping using z-shim multi-echo gradient echo imaging.

Dongyeob Han1, Yoonho Nam, Sung-Min Gho

  • 1Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea.

Magnetic Resonance in Medicine
|March 26, 2014
PubMed
Summary
This summary is machine-generated.

This study introduces a new 3D z-shim method for accurate R2* mapping, improving magnetic field inhomogeneity correction and enhancing image quality in vivo.

Keywords:
3D z-shimR2* mappingmacroscopic B0 field inhomogeneity

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Area of Science:

  • Magnetic Resonance Imaging
  • Quantitative MRI

Background:

  • Accurate R2* mapping is crucial for various MRI applications.
  • Macroscopic B0 field inhomogeneity can significantly degrade R2* quantification accuracy.

Purpose of the Study:

  • To develop and validate a macroscopic B0 field inhomogeneity-compensated volumetric R2* mapping method.
  • To utilize a three-dimensional (3D) z-shim multi-echo acquisition for improved R2* estimation.

Main Methods:

  • A novel z-shim sequence alternating conventional and z-shimmed echoes with bipolar readout gradients.
  • Application of a constant-valued z-shim gradient before negative readout gradient lobes.
  • Development of a phase combination algorithm for B0 inhomogeneity-compensated field mapping.
  • Utilizing a modified signal model for 3D R2* quantification.

Main Results:

  • Phantom experiments demonstrated an increased range of field inhomogeneity correction.
  • In vivo studies showed enhanced R2* map quality across different subjects.
  • The proposed method effectively compensates for B0 field inhomogeneities.

Conclusions:

  • The developed 3D z-shim method significantly improves R2* estimation accuracy.
  • Enhanced R2* mapping is particularly notable in the frontal and temporal brain regions.
  • This technique offers improved quantitative MRI capabilities.