¹⁸F-fluoride PET/computed tomography imaging
1Department of Nuclear Medicine, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv 64239, Israel.
18F-fluoride PET/CT imaging is a sensitive tool for assessing bone abnormalities in both cancer and benign conditions. Its increasing availability makes it valuable for evaluating skeletal lesions and bone pathophysiology in clinical practice.
Area of Science:
- Nuclear Medicine
- Radiology
- Oncology
Background:
- The proliferation of cyclotrons and PET/CT scanners enhances the accessibility of 18F-fluoride PET/CT.
- 18F-fluoride PET/CT is a well-established imaging modality for bone assessment.
Purpose of the Study:
- To advocate for the broader clinical consideration of 18F-fluoride PET/CT.
- To highlight its utility in evaluating bone abnormalities across various clinical scenarios.
Main Methods:
- Review of accumulated data on 18F-fluoride PET/CT imaging.
- Analysis of its sensitivity and scope in detecting skeletal lesions.
Main Results:
- 18F-fluoride PET/CT demonstrates high sensitivity for detecting skeletal lesions.
- The modality effectively assesses pathophysiologic processes in both normal and abnormal bone.
Conclusions:
- 18F-fluoride PET/CT imaging should be integrated into routine clinical practice.
- Its application extends beyond oncology to encompass benign bone conditions.
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