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Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
Published on: August 19, 2012
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Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry
1Institute of Integrative Biology, University of Liverpool, Crown Street, Liverpool, UK L69 7ZB. dgfernig@liv.ac.uk.
Chemical Communications (Cambridge, England)
|September 18, 2014
Abstract:
A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.
