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Updated: Apr 23, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Epidemiology, risk factors, prevention, and early detection of melanoma
Saïd C Azoury1, Julie R Lange1
1Department of Surgery, The Johns Hopkins Hospital, Johns Hopkins Medicine, 600 North Wolfe Street, Blalock 610, Baltimore, MD 21287, USA.
Abstract:
The incidence of melanoma has increased over the past several decades. Despite improved case mortality, overall deaths from melanoma have increased because of the large increase in incidence. Although we have a better understanding of the pathogenesis of melanoma and improved early diagnostic capabilities, the burden of disease and societal costs remain high. This article provides an update on the epidemiology of cutaneous melanoma worldwide and the common risk factors including heritable and modifiable risks, emphasizing the importance of education, early detection, and prevention in reducing the disease burden.
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