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Updated: Apr 22, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Idiopathic pulmonary haemosiderosis in a one-year-old girl with Down syndrome]
Anna Elisabeth Lewis1, Christina Engel Høi-Hansen, Frederik Buchvald
1Børne- og Ungeafdelingen, Nordsjællands -Hospital, Hillerød, Dyrehavevej 29, 3400 Hillerød.
Abstract:
Idiopathic pulmonary haemosiderosis (IPH) is a rare disease. We describe a girl with Down syndrome who had no major respiratory symptoms until one year of age, where recurrent airway infections and chronic anaemia of unknown aetiology developed. At 20 months of age she had intermittent haemo-ptysis, was investigated with computed tomography and broncho-alveolar lavage and was diagnosed with IPH. After treatment, respiratory symptoms and anaemia resolved and a positive impact on previously impaired growth and psychomotor development was seen. Paediatricians should consider IPH in children with recurrent respiratory symptoms and anaemia.
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