Mesenchymal stem cells from human dental pulp: isolation, characteristics, and potencies of targeted differentiation
R A Poltavtseva1, Yu A Nikonova, I I Selezneva
1V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia, rimpol@mail.ru.
Bulletin of Experimental Biology and Medicine
|November 20, 2014
Abstract:
We studied cell cultures isolated from the pulp of third molar germ of an adult human and from the skin of a human fetus on gestation day 10. Both cultures expressed similar repertoire of surface markers typical of multipotent mesenchymal cells (CD44, CD90, and CD105). Under in vitro conditions, dental pulp cells were more susceptible to factors inducing their differentiation into adipogenic, chondrogenic, and osteogenic lineage cells.
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