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Synthesis and characterization of cell-microenvironment-sensitive leakage-free gold-shell nanoparticles with the
Jian Dai1, Qianqian Li, Wenya Liu
1School of Engineering, Sun Yat-sen University, Guangzhou 510006, P. R. China. daijian@mail.sysu.edu.cn.
Chemical Communications (Cambridge, England)
|May 16, 2015
Abstract:
Novel gold-shell nanoparticles (pH-GSNPs) are designed for the first time, which exhibit drug leakage-free behavior in a physiological environment, while achieving rapid drug release and remarkable aggregation for the nanogold interlayer of pH-GSNPs to shift their absorption to far-red and NIR as a photothermal agent in the intracellular microenvironment.
