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Updated: Apr 11, 2026

03:55
A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
Published on: June 27, 2022
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A highly selective and fast-response fluorescent probe for visualization of enzymatic H2S production in vitro and in
Lv Wei1, Zhentao Zhu, Yanyan Li
1State Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin, 300071, China. zhenxi@nankai.edu.cn.
Abstract:
An o-fluorinated-azido-capped rhodamine probe can react with H2S efficiently and selectively to give large off-on fluorescence enhancement. The probe was used to develop an assay for cystathionine β-synthase acitivity and for in situ visualization of endogenously produced H2S in living cells.

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