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Updated: Apr 4, 2026

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging
Published on: July 19, 2016
Several hundred-fold enhanced fluorescence from single fluorophores assembled on silver nanoparticle-dielectric-metal
Krishanu Ray1, Ramachandram Badugu, Henryk Szmacinski
1Centre for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201, USA. kray@som.umaryland.edu.
Abstract:
We observed over 400-fold enhanced fluorescence from single Cy5 molecules assembled on multilayer silver nanoparticle-dielectric-metal (PDM) substrate. This substantial enhancement is due to the near-field enhanced excitation, emission, and interaction of Cy5 with plasmonic nanostructures. Experimental observation is supported by finite-element method calculations.

