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Updated: Apr 3, 2026

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
Published on: October 6, 2023
[THE STATUS OF CERTAIN PHYSIOLOGICAL ADRENERGIC RESPONSES IN ALBINO RATS DURING DEVELOPMENT OF EXPERIMENTAL
Abstract:
In this paper we investigated the effects of thyroid hormones on the expression of physiological reactions during adrenergic stimulation (20 min at a dose of 2.0 mg x kg(-1) x min(-1)) during the development of experimental hyperthyroidism. Rats were divided into two groups. The animals in Group 1 were injected woth triiodothyronine. The duration of injection ranged from 1 to 12 days. Consequently, 12 subgroups were formed. The second group was the control group. It is shown that in the process of development of experimental hyperthyroidism all physiological responses vary in accordance with the law, which can be described by a parabola of general form with the value of the degree in the equation equal to three.
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