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Updated: Mar 29, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
Radiosurgery for Medial Temporal Lobe Epilepsy Resulting from Mesial Temporal Sclerosis
Thomas Gianaris1, Thomas Witt1, Nicholas M Barbaro1
1Department of Neurological Surgery, Indiana University School of Medicine, 355 W. 16th St., Suite 5100, Indianapolis, IN 46202, USA.
Abstract:
Medial temporal lobe epilepsy associated with mesial temporal sclerosis (MTS) is perhaps the most well-defined epilepsy syndrome that is responsive to structural interventions such as surgery. Several minimally invasive techniques have arisen that provide additional options for the treatment of MTS while potentially avoiding many of open surgery's associated risks. By evading these risks, they also open up treatment options to patients who otherwise are poor surgical candidates. Radiosurgery is one of the most intensively studied of these alternatives and has found a growing role in the treatment of medial temporal lobe epilepsy.

