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A nanocluster beacon based on the template transformation of DNA-templated silver nanoclusters
Ye Teng1, Xiaofang Jia, Shan Zhang
1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. ekwang@ciac.ac.cn.
Chemical Communications (Cambridge, England)
|December 16, 2015
Abstract:
In this work, we developed a novel light-up nanocluster beacon (NCB) based on shuttling dark silver nanoclusters (NCs) to a bright scaffold through hybridization. The fluorescence enhancement was as high as 70-fold when the two templates were on the opposite sides of the duplexes, enabling sensitive and selective detection of DNA.
