[The application progress of three-dimensional cell culture technology in ophthalmology]

Three-dimensional cell culture technology is a kind of technology that cultures the cells in a three-dimensional cultivation by using a kind of scaffold materials in vitro. Its advantage is that the vivo microenvironment simulating degrees of the three-dimensional culture technology is higher than that of the two-dimensional planar cell culture model, and the controllability is also higher than the animal experiment. In recent years, with the development of tissue engineering technology, a varietiy of the stent of biological materials also a fast development, which provided a favorable platform for three-dimensional cell culture technology. In ophthalmology, three-dimensional cell culture has been applied to the cornea, retina and the visual system development and other optic tumor researches. The objective of this paper is to making a review the application status of the three-dimensional cell culture technology in the basic research and clinical treatment in ophthalmology.