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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
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Related Experiment Video

Updated: Mar 24, 2026

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
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Relationship between removable prosthesis and some systemics disorders.

Pierre Le Bars1, Alain Ayepa Kouadio2, Justin Koffi N'goran3

  • 1Department of Prosthodonthics, Faculty of Dentistry, CHU Nantes, 1 Place Alexis Ricordeau, 44042 Nantes, France.

Journal of Indian Prosthodontic Society
|March 2, 2016
PubMed
Summary
This summary is machine-generated.

Patients with systemic diseases wearing removable dentures may have increased oral Candida albicans. Enhanced oral hygiene and professional care are recommended for these medically compromised individuals.

Keywords:
Cardiovascular diseasesdiabetes mellitusgastrointestinal diseaseshuman immunodeficiency viruspulmonary diseasesremovable prosthesis

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Area of Science:

  • Oral health
  • Systemic diseases
  • Prosthodontics

Background:

  • Removable prosthesis (RP) use is common, but its impact on patients with systemic diseases is not fully understood.
  • Certain systemic conditions may influence oral health outcomes in denture wearers.
  • Candida albicans is a common oral fungus that can cause opportunistic infections.

Purpose of the Study:

  • To review the dental literature on the impact of removable prosthesis on patients with specific systemic diseases.
  • To investigate the association between removable prosthesis use and six systemic pathologies.
  • To identify potential oral health risks in medically compromised denture wearers.

Main Methods:

  • A literature survey was conducted using Medline/PubMed and manual searches up to 2015.
  • Keywords focused on the association between removable prosthesis and Human immunodeficiency virus infection, diabetes mellitus, pulmonary diseases, gastric-Helicobacter pylori, cancer, and cardiovascular diseases.
  • Analysis of selected articles to determine the prevalence of oral Candida albicans.

Main Results:

  • Patients with removable prosthesis and one or more of the six systemic conditions showed a higher frequency of Candida albicans in oral flora compared to healthy denture wearers.
  • Causality between systemic diseases and increased oral candidiasis in denture patients remains unestablished.
  • The relationship between general diseases and increased oral candidiasis in denture patients requires further explanation.

Conclusions:

  • Medically compromised patients wearing removable prosthesis may have an increased risk of oral candidiasis.
  • Strengthening hygienic practices is crucial for patients with systemic diseases, especially those with disabilities.
  • Attention to oral hygiene and professional care for removing Candida albicans may benefit these patients.