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RECIST Applied to Realistic Tumor Models
Zachary H Levine1, Benjamin R Galloway1, Adele P Peskin2
1Optical Technology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899-8441.
Abstract:
RECIST (Response Evaluation Criteria in Solid Tumors) is a linear measure intended to predict tumor size in medical computed tomography (CT). In this work, using purely geometrical considerations, we estimate how well RECIST can predict the volume of randomly-oriented tumor models, each composed of the union of ellipsoids. The principal conclusion is that RECIST is likely to work less well for realistic tumors than for ellipsoids.
