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Updated: Mar 23, 2026

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
Acute Cardiopulmonary and Metabolic Responses to High-Intensity Interval Training Protocols Using 60 s of Work and 60
Ralph Rozenek1, James W Salassi, Nicole M Pinto
1CSULB KIN Exercise Physiology Laboratory, Department of Kinesiology, Long Beach, California.
High-intensity interval training (HIIT) protocols using 60-second work and 60-second recovery periods elicit significant cardiopulmonary and metabolic responses. Different work and recovery intensity combinations impact these acute physiological changes during training sessions.
Area of Science:
- Exercise Physiology
- Sports Science
- Cardiopulmonary Function
Background:
- Low-volume, high-intensity interval training (HIIT) with 60-second work/60-second recovery (60s/60s) promotes beneficial adaptations.
- Limited data exists on the acute physiological responses during individual HIIT sessions.
Purpose of the Study:
- To investigate the acute physiological responses to 60s/60s x 10 HIIT protocols with varied work and recovery intensities.
- To compare the effects of different intensity combinations on cardiopulmonary and metabolic markers.
Main Methods:
- Eleven healthy adults completed four HIIT trials with varying peak power output (PPO) intensities: 80% PPO/0% PPO (80/0), 80% PPO/50% PPO (80/50), 100% PPO/0% PPO (100/0), and 100% PPO/50% PPO (100/50).
- Physiological responses including oxygen consumption (V[Combining Dot Above]O2peak), heart rate (HRpeak), rating of perceived exertion (RPE), and blood lactate were measured.
Main Results:
- The 100% PPO/50% PPO (100/50) protocol resulted in significantly higher peak, average, and nadir %V[Combining Dot Above]O2peak compared to other protocols.
- Most protocols elicited %V[Combining Dot Above]O2peak and %HRpeak values within recommended ranges for improving cardiopulmonary function.
- The 80/50 protocol showed a significantly higher average %V[Combining Dot Above]O2peak (approximately 9.3% absolute) than the 100/0 protocol, despite similar HR, RPE, and blood lactate levels.
Conclusions:
- The 100/50 HIIT protocol induces the greatest acute cardiopulmonary stress.
- Protocols like 80/0, 80/50, and 100/0 are suitable for individuals with low to moderate cardiopulmonary fitness.
- Understanding acute responses informs the selection of appropriate HIIT protocols for different fitness levels.
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