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Published on: August 17, 2022
Short Term Donor Outcomes After Hepatectomy in Living Donor Liver Transplantation
Faisal Saud Dar1, Haseeb Zia1, Abu Bakar Hafeez Bhatti1
1Department of HPB and Liver Transplantation, Shifa International Hospital, Islamabad.
Objective:
To determine the outcome of living-donor liver transplant (LDLT) donors from the first liver transplant program in Pakistan.
Study Design:
Cohort study.
Place And Duration Of Study:
Shifa International Hospital, Islamabad, from April 2012 to August 2014.
Methodology:
A total of 100 live donors who underwent hepatectomy were included. Demographics, etiologies, graft characteristics and operative variables were retrospectively assessed. Outcome was assessed based on morbidity and mortality.
Results:
Median donor age was 28 (17 - 45) years and median body mass index (BMI) was 24 kg/m2 (15 - 36). Male to female ratio was 1.5:1. Hepatitis B and C were the most common underlying etiologies and accounted for 79/100 (79%) of LDLT's. Overall, 93/100 (93%) donors donated a right lobe graft. Median estimated graft weight to recipient body weight (GW/BW) ratio was 1.03 (0.78 - 2). Standard arterial anatomy was present in 56% donors. The 90-day morbidity was 13/100 (13%) and overall morbidity was 17/100 (17%). Bile leak was encountered in 3 (3%) patients. There was no donor mortality.
Conclusion:
Acceptable short-term donor outcomes were achieved in an LDLT program in Pakistan with careful donor selection and planning.
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