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Published on: June 24, 2025
A Program to Prevent Catheter-Associated Urinary Tract Infection in Acute Care.
Sanjay Saint1, M Todd Greene1, Sarah L Krein1
1From the Hospital Outcomes Program of Excellence, Veterans Affairs (VA) Ann Arbor Healthcare System (S.S., M.T.G., S.L.K., D.R., K.E.F.), the Department of Internal Medicine, University of Michigan (UM) Medical School (S.S., M.T.G., S.L.K., M.A.M.R.), and the VA/UM Patient Safety Enhancement Program (S.S., M.T.G., S.L.K., M.A.M.R., D.R., K.E.F.), Ann Arbor, the Michigan Health and Hospital Association, Okemos (S.R.W., B.M.-L., M.M.), and St. John Hospital and Medical Center, Detroit (M.G.F.) - all in Michigan; the Health Research and Educational Trust, Chicago (B.S.E., K.F.); the Centers for Disease Control and Prevention, Atlanta (C.V.G.); and the Agency for Healthcare Research and Quality, Rockville, MD ( J.B.).
A national program effectively reduced catheter-associated urinary tract infections (UTIs) in non-intensive care units by focusing on both technical and behavioral changes. This initiative demonstrated significant decreases in catheter use and infection rates, improving patient safety.
Area of Science:
- Healthcare-associated infections
- Patient safety initiatives
- Infection prevention and control
Background:
- Catheter-associated urinary tract infection (UTI) is a prevalent hospital-acquired infection.
- Prevention requires attention to both technical aspects of catheter use and socio-behavioral factors within hospital units.
Purpose of the Study:
- To evaluate the impact of a national prevention program on catheter-associated UTI rates and catheter use in intensive care units (ICUs) and non-ICUs.
- To assess the effectiveness of a program emphasizing technical and socio-behavioral strategies for UTI prevention.
Main Methods:
- The Comprehensive Unit-based Safety Program disseminated information and guidance on UTI prevention strategies.
- Data on catheter use and catheter-associated UTI rates were collected across 926 units in 603 hospitals.
- Multilevel negative binomial models analyzed changes in rates during baseline, implementation, and sustainability phases.
Main Results:
- Overall catheter-associated UTI rates decreased from 2.82 to 2.19 per 1000 catheter-days (unadjusted) and 2.40 to 2.05 (adjusted).
- In non-ICUs, catheter use decreased by 7.3% and catheter-associated UTI rates fell by 32.5%.
- Significant reductions were observed in non-ICUs, while rates remained largely unchanged in ICUs, indicating differential program effectiveness.
Conclusions:
- A national prevention program successfully reduced catheter use and catheter-associated UTI rates, particularly in non-ICU settings.
- The findings support the integration of technical and socio-behavioral interventions for effective UTI prevention in hospitals.
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