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A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging
Published on: February 4, 2022
Vascular Disorders of the Cerebellum in Children
Reade A De Leacy1, Alejandro Berenstein2, Thomas P Naidich3
1Department of Neurosurgery, Cerebrovascular Center, Mount Sinai Hospital, Mount Sinai Medical Center, KCC 1-North, 1450 Madison Avenue, New York, NY 10029, USA; Department of Radiology, Cerebrovascular Center, Mount Sinai Hospital, Mount Sinai Medical Center, KCC 1-North, 1450 Madison Avenue, New York, NY 10029, USA.
Insights
Pediatric cerebellar vascular lesions differ from adult types in cause, presentation, and imaging. Understanding these distinctions is crucial for accurate diagnosis and effective treatment in children.
Area of Science:
- Neuroimaging
- Pediatric Neurology
- Vascular Malformations
Background:
- Cerebellar vascular lesions present differently in children and adults regarding epidemiology, pathophysiology, and clinical signs.
- Distinguishing normal vascular variations from pathology is essential for proper diagnosis and management.
Purpose of the Study:
- To review the embryogenesis of the normal cerebellum and brainstem vascular system.
- To discuss the clinical and imaging features of common vascular lesions in the pediatric population.
Main Methods:
- Review of embryogenesis of cerebellar and brainstem vasculature.
- Discussion of clinical presentations of pediatric vascular lesions.
- Analysis of characteristic imaging findings in pediatric cerebellar vascular lesions.
Main Results:
- Key differences in vascular lesion characteristics exist between pediatric and adult populations.
- Distinct imaging features aid in differentiating normal variants from pathology.
- Understanding these features helps predict etiology and guide treatment.
Conclusions:
- Knowledge of pediatric-specific vascular lesion features is vital for accurate diagnosis.
- Imaging analysis is critical for identifying and characterizing these lesions in children.
- Effective treatment strategies depend on understanding the unique aspects of pediatric cerebellar vascular lesions.
Abstract:
Key differences exist in the epidemiology, pathophysiology, and clinical presentation of vascular lesions of the cerebellum in children versus adults. An understanding of these differences and an appreciation of the distinct imaging features of these lesions aid in distinguishing normal vascular variations from pathology, in predicting lesion etiology, and in directing effective treatment strategies. This paper reviews the embryogenesis of the normal vascular system of the cerebellum and brainstem and then discusses the clinical and imaging features of the common vascular lesions affecting these structures in the pediatric population.
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