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Pharmacology in the Geriatric Patient

Katherine Louise Welker1, Mark B Mycyk1

  • 1Department of Emergency Medicine, Cook County Health and Hospitals System, 1900 West Polk Street, Chicago, IL 60612, USA.

Emergency Medicine Clinics of North America
|August 1, 2016
PubMed

Keywords:
AgingClinical pharmacistsDrug interactionsPolypharmacy

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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