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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

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Management of Desmoids.

Valerie P Grignol¹, Raphael Pollock¹, John Harrison Howard¹

¹Division of Surgical Oncology, Department of Surgery, The Ohio State University, N924 Doan Hall, 410 West 10th Avenue, Columbus, OH 43210, USA.

The Surgical Clinics of North America

|August 21, 2016

Summary

Desmoid tumors, rare soft tissue neoplasms, are increasingly managed with watchful waiting due to observed stability and spontaneous regression. Surgical resection remains an option, but recurrence rates necessitate multimodal therapies for disease control.

Keywords:

Beta-catenin Desmoid fibromatosis Management Margins Observation

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Area of Science:

Oncology
Surgical Pathology
Soft Tissue Neoplasms

Background:

Desmoid tumors represent 3% of all soft tissue tumors.
Historically, surgical resection was the primary treatment.
Evolving treatment paradigms now include active surveillance.

Purpose of the Study:

To review the current management strategies for desmoid tumors.
To highlight the shift towards conservative management.
To discuss the role of surgery and multimodal therapies.

Main Methods:

Observational studies analyzing long-term tumor behavior.
Review of surgical outcomes and recurrence rates.
Evaluation of multimodal therapeutic approaches.

Main Results:

Many desmoid tumors exhibit long-term stability without intervention.
Spontaneous regression occurs in 5% to 10% of cases.
Surgical resection aims for negative margins but must preserve function; recurrence rates are around 20%.

Conclusions:

Watchful waiting is a viable management option for desmoid tumors.
Surgical resection requires careful consideration of functional outcomes.
Multimodal therapies are crucial for managing recurrent or persistent disease.