A Shake&Read distance-based microfluidic chip as a portable quantitative readout device for highly sensitive
Yi Xie1, Xiaofeng Wei2, Qizhen Yang3
1MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China. cyyang@xmu.edu.cn zhuzhi@xmu.edu.cn.
Abstract:
Despite the rapid development of point-of-care testing (POCT) devices in recent years, quantitative POCT is still not readily available. Herein, we developed a simple, disposable and equipment-free quantitative POCT platform, the Shake&Read distance-based microfluidic Chip (S&R-μChip), for visual quantitative POCT and demonstrated its use in Enzyme-Linked Immunosorbent Assay (ELISA) for the detection of disease biomarkers.
