Related Experiment Video
Updated: Mar 12, 2026
Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
Published on: August 4, 2018
MULTICOLOR SCANNING LASER IMAGING IN LIPEMIA RETINALIS
David Rivera-De La Parra1, Liliana Perez-Peralta, Jim Toldi
1*Centro de atención integral del paciente con diabetes, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico; †Instituto de Oftalmología "Fundación Conde de Valenciana" I.A.P., Mexico City, Mexico; ‡Florida State University College of Medicine, Bonita Springs, Florida; §Arizona Eye Consultants, Tucson, Arizona; and ¶Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, California.
Multicolor scanning laser imaging (MSLI) offers a more detailed view of retinal changes in lipemia retinalis (LR) than conventional fundus photography. MSLI can aid in diagnosing and monitoring this condition, especially in diabetic patients.
Area of Science:
- Ophthalmology
- Medical Imaging
- Endocrinology
Background:
- Lipemia retinalis (LR) is a rare condition characterized by milky-appearing retinal vessels due to high triglyceride levels.
- Diabetes mellitus is a common comorbidity associated with hypertriglyceridemia and LR.
- Early detection and monitoring of LR are crucial for managing underlying metabolic disorders.
Observation:
- This study describes two cases of lipemia retinalis in diabetic patients.
- Multicolor scanning laser imaging (MSLI) and conventional fundus photography were used to evaluate retinal findings.
- Optical coherence tomography (OCT) was also employed in one case.
Findings:
- MSLI revealed intense yellow retinal arteries and pale yellow retinal veins in one patient.
- Conventional fundus photography showed only mild, pale red vessels in both cases.
- OCT identified macular edema and hyperreflective retinal vessel changes in the first case.
- Retinal vessel appearance normalized in the second case after achieving metabolic control.
Implications:
- MSLI provides more significant findings for diagnosing and monitoring lipemia retinalis compared to conventional fundus photography.
- Enhanced visualization of retinal vasculature with MSLI can improve patient management.
- This study highlights the utility of advanced imaging techniques in ophthalmology for metabolic-related conditions.
