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Updated: Mar 10, 2026

Controlled Photoredox Ring-Opening Polymerization of O-Carboxyanhydrides Mediated by Ni/Zn Complexes
Published on: November 21, 2017
Copper-Catalyzed Regioselective Ring-Opening Hydroamination of Methylenecyclopropanes
Daiki Nishikawa1, Ryosuke Sakae1, Yuya Miki1
1Department of Applied Chemistry, Graduate School of Engineering, Osaka University , Suita, Osaka 565-0871, Japan.
Abstract:
A copper-catalyzed ring-opening hydroamination of methylenecyclopropanes with polymethylhydrosiloxane and O-benzoylhydroxylamines has been developed. The cyclopropane C-C bond cleavage occurs selectively at the more congested proximal position, and the corresponding homoallylamines are obtained in good to excellent yields. The umpolung electrophilic amination strategy with the hydroxylamine derivatives can provide a new reaction mode of methylenecyclopropanes in the catalytic hydroamination reaction.
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