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Published on: September 27, 2013
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Technical Considerations for Filler and Neuromodulator Refinements.
José Raúl Montes1, Anthony J Wilson1, Brian L Chang1
1Department of Ophthalmology, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico; and Division of Plastic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.
Plastic and Reconstructive Surgery. Global Open
|December 27, 2016
Summary
Cosmetic practitioners can achieve optimal patient outcomes by customizing neurotoxin and soft-tissue filler treatments. Understanding product properties and evidence-based techniques ensures safe, natural-looking results in facial aesthetics.
Area of Science:
- Dermatology
- Cosmetic Surgery
- Aesthetic Medicine
Background:
- The cosmetic industry offers a rapidly expanding array of novel neurotoxins and soft-tissue fillers.
- Physicians face challenges in selecting optimal products and techniques for patient outcomes.
- Off-label indications for injectables are continuously increasing.
Purpose of the Study:
- To review Food and Drug Administration-approved facial injectables based on evidence-based medicine.
- To evaluate product properties and their suitability for specific indications.
- To provide clinical commentary on refined techniques for neuromodulators and soft-tissue fillers.
Main Methods:
- Conducted a PubMed literature search of facial injectables from 2005-2015.
- Focused on evidence-based articles and physicochemical properties of products.
- Included expert commentary on clinical experience and technical refinements.
Main Results:
- Neurotoxins and fillers possess unique physical characteristics influencing clinical applications.
- Specific indications and product recommendations are detailed.
- Refinements in combination treatments and product modifications for various facial zones are highlighted.
Conclusions:
- Facial aesthetics has advanced significantly due to a better understanding of 3D volume restoration.
- Product customization is safe and effective for specific indications like mid-face, décolletage, hands, and periorbital areas.
- Customized injectable treatments yield natural results and excellent patient outcomes.

