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Updated: Mar 8, 2026

Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension
Published on: June 27, 2025
Contractility of Right Ventricular Myocardium in Male and Female Rats during Physiological and Pathological
Yu L Protsenko1, A A Balakin1, D A Kuznetsov1
1Institute of Immunology and Physiology, Ural Division of Russian Academy of Sciences, Ekaterinburg, Russia.
Abstract:
Sex differences in the morphogenesis and adaptation of the mechanisms controlling myocardium contractility during physiological and pathological hypertrophy of the right ventricle were demonstrated in mature rats. The study revealed sex-dependent effects of physiological and pathological cardiac hypertrophy on the coefficient of variation of the cardiomyocyte diameter, length-dependent control of the contractile force, and the maximum velocity of isotonic shortening.
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