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Annular rectal constriction caused by infiltrating bladder cancer: A case report
Hisashi Takeuchi1, Naoto Tokuyama1, Isao Kuroda1
1Department of Urology, Tokyo Medical University Ibaraki Medical Center, Ibaraki 300-0395, Japan.
Molecular and Clinical Oncology
|January 21, 2017
Summary
This study reports a rare case of bladder cancer invading the rectum, causing urinary and bowel symptoms. Chemotherapy with gemcitabine and cisplatin showed effective treatment for this advanced urothelial carcinoma.
Area of Science:
- Urology
- Oncology
- Medical Imaging
Background:
- Urothelial carcinoma, a common bladder cancer, can rarely present with rectal invasion.
- Symptoms like urinary incontinence and bowel changes can indicate advanced disease.
Purpose of the Study:
- To present a case of advanced urothelial carcinoma with rectal infiltration.
- To highlight diagnostic challenges and treatment efficacy.
Main Methods:
- Case report of a 69-year-old male with relevant symptoms.
- Diagnostic workup included imaging (CT, MRI) and biopsies.
- Tumor markers (CEA, CA19-9) were assessed.
- Treatment involved gemcitabine and cisplatin chemotherapy.
Main Results:
- Imaging revealed bilateral hydronephrosis, rectal/bladder wall thickening, and lymphadenopathy.
- Biopsies confirmed grade 2 urothelial carcinoma with glandular differentiation and rectal infiltration.
- Annular rectal constriction due to infiltrating bladder cancer was diagnosed.
- Three cycles of chemotherapy demonstrated good efficacy.
Conclusions:
- Advanced urothelial carcinoma can infiltrate adjacent organs like the rectum.
- Multimodal diagnostic approaches are crucial for accurate staging.
- Combination chemotherapy offers a viable treatment option for such complex cases.
