STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF BENIGN FLECK RETINA USING MULTIMODAL IMAGING.
Srividya Neriyanuri1, Chetan Rao, Rajiv Raman
1*Elite School of Optometry, Chennai, India;†Birla Institute of Science and Technology, Pilani, India; and‡Shri Bhagwan Mahaveer Vitreoretinal services, Sankara Nethralaya, Chennai, India.
Multimodal imaging revealed structural and functional deficits in benign fleck retina, even in visually asymptomatic patients. This approach aids in understanding the condition
Area of Science:
- Ophthalmology
- Retinal Imaging
- Genetic Eye Diseases
Background:
- Benign fleck retina is a rare inherited retinal disorder.
- Characterized by distinct retinal flecks, its precise structural and functional impact requires detailed investigation.
Observation:
- A case series of four patients with benign fleck retina was studied.
- Comprehensive ophthalmic examinations included multimodal imaging techniques.
Findings:
- Multimodal imaging demonstrated pisciform flecks with specific autofluorescence and fluorescein angiography patterns.
- Optical coherence tomography revealed lesions at various retinal layers, from the retinal pigment epithelium to the external limiting membrane.
- While most patients were asymptomatic with good visual acuity, some exhibited reduced color discrimination and altered electroretinogram responses.
Implications:
- Multimodal imaging is crucial for detecting subtle structural and functional abnormalities in benign fleck retina.
- This imaging approach can aid in early diagnosis and monitoring of the disease progression.
- Understanding these deficits contributes to the broader knowledge of inherited retinal dystrophies.
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