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TRPC Channels and Alzheimer's Disease.

Rui Lu1, Qian He1, Junfeng Wang2

  • 1Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, China.

Advances in Experimental Medicine and Biology
|May 17, 2017
PubMed
Summary

Transient Receptor Potential Canonical (TRPC) channels, particularly TRPC6, show involvement in Alzheimer's disease (AD) pathogenesis. Targeting these TRPC channels presents a potential therapeutic strategy for AD.

Keywords:
Alzheimer’s diseaseCalciumTRPC6β-amyloid

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