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Does Bariatric Surgery Improve Obesity Associated Comorbid Conditions
Atilla Engin1,2
1Faculty of Medicine, Department of General Surgery, Gazi University, Besevler, Ankara, Turkey. dr.aengin@gmail.com.
Advances in Experimental Medicine and Biology
|June 7, 2017
Summary
Bariatric surgery offers substantial and durable weight loss for obesity when conservative methods fail. However, the long-term metabolic and inflammatory effects of this weight loss require further investigation.
Area of Science:
- Metabolic disorders
- Surgical interventions
Background:
- Obesity is a growing global health concern impacting quality of life and longevity.
- Conservative treatments for obesity often prove insufficient, necessitating advanced interventions.
- Bariatric surgery is considered when other methods fail to achieve significant weight reduction.
Purpose of the Study:
- To compare the efficacy of multidisciplinary programs versus bariatric surgery for weight loss.
- To evaluate the durability of weight reduction achieved through surgical interventions.
- To explore the ongoing debate regarding the metabolic and inflammatory consequences of bariatric-induced weight loss.
Main Methods:
- Comparative analysis of weight loss outcomes.
- Assessment of multidisciplinary program effectiveness.
- Evaluation of bariatric surgical treatment results.
Main Results:
- Bariatric surgical treatments demonstrated substantial and durable weight reduction compared to multidisciplinary programs.
- Significant weight loss was primarily achieved through surgical interventions.
Conclusions:
- Bariatric surgery is a highly effective treatment for achieving significant and lasting weight loss in obesity.
- Further research is needed to fully understand the pro-inflammatory and metabolic profile changes post-bariatric surgery.
Keywords:
AdiponectinAnemiaApelinBariatric surgeryC-reactive proteinEndothelial nitric oxide synthase (eNOS)GhrelinGlutathioneHomocysteineInducible nitric oxide synthase (iNOS)Insulin resistanceInterleukin 6 (IL-6)LeptinLysyl oxidase (LOX)ObesityOxidative stressResistinRetinol-binding protein-4 (RBP4)Roux-en-Y gastric bypassSleeve gastrectomyTotal cysteine (tCys)TriglyceridesVaspinVisfatinWeight loss
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