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HTLV-1 infection in Reunion
G Hoarau1, B A Gaüzère2, H Renard3
1Service de microbiologie, CHU de la Réunion, BP 350, 97448 Saint-Pierre, Reunion.
Medecine Et Maladies Infectieuses
|June 28, 2017
Summary
Human T-lymphotropic virus (HTLV) infections are rare in Reunion, but local circulation and symptomatic cases, including TSP/HAM and ATLL, were identified. This study describes the HTLV epidemiology in the region.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Human T-lymphotropic virus (HTLV) is a retrovirus with global prevalence.
- HTLV infections are typically screened for in blood donors but are rare in Reunion.
- Understanding local HTLV epidemiology is crucial for public health strategies.
Observation:
- A retrospective analysis of HTLV infections was conducted using Reunion University Hospital administrative data from 2000 to 2016.
- Diagnostic methods included HTLV 1/2 enzyme immunoassay and Western blot confirmation.
- Seven HTLV infections were identified during the study period.
Findings:
- Three asymptomatic and four symptomatic HTLV infections were reported.
- Symptomatic cases included two instances of tropical spastic paraparesis/HTLV-1 associated myelopathies (TSP/HAM).
- Two cases of adult T-cell leukemia/lymphoma (ATLL) were also diagnosed.
Implications:
- Reunion is confirmed as a low HTLV prevalence area, potentially due to its unique settlement history.
- The findings highlight the ongoing local circulation of HTLV.
- The presence of symptomatic HTLV infections underscores the need for continued surveillance and awareness.
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