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Updated: Feb 26, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
[Genomic medicine : the challenges of information in clinical practice]
Idris Guessous1,2, Vincent Mooser3, Jacques Fellay4
1PMU, Université de Lausanne, 1011 Lausanne.
Abstract:
The genomic revolution lifts up several potential opportunities in predictive and preventive medicine. Yet, genomic medicine opportunities can lead to clinical utility only if challenges that come with it are understood, anticipated, and faced. This review discusses the challenges that genomic medicine raises for the patients and their physicians, the general population, study participants and investigators. The article presents a program of genomic consultation in general internal medicine in the French-speaking part of Switzerland (MedOmics) that aims to address these challenges in order to optimize the clinical opportunities offered by genomic medicine.
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