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Updated: Feb 22, 2026
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
Combining Functional Studies with Intraoperative MRI in Glioma Surgery
Daria Krivosheya1, Sujit S Prabhu2
1Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Division of Neurosurgery, Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, 339 Windermere Road, London, ON N6A 5A5, Canada.
Abstract:
Maximal safe resection is the cornerstone of treatment for low-grade and high-grade gliomas. In addition to high-resolution anatomic MRI studies that highlight tumor architecture, it is important to determine the relationship of the tumor to the eloquent cortical and subcortical areas to avoid introducing or exacerbating a neurologic deficit. The goal of this review was to highlight imaging modalities that provide functional information and can be integrated with intraoperative MRI navigation to maximize the extent of resection while preserving a patient's neurologic function.
