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Maxillary Sinus Floor Augmentation Using an Equine-Derived Graft Material: Preliminary Results in 17 Patients
F Rivara1, M Negri2, S Lumetti1
1Dipartimento di Medicina e Chirurgia, Centro di Odontoiatria, Università di Parma, Parma, Italy.
Biomed Research International
|December 7, 2017
Summary
An equine-derived bone graft effectively promotes new bone formation in sinus floor elevation procedures. Histomorphometric analysis of human biopsies revealed significant bone regeneration and graft remodeling after six months.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Medicine
- Biomaterials Science
Background:
- Sinus floor elevation is a common procedure to address bone deficiency in the posterior maxilla.
- Various bone graft materials have demonstrated clinical efficacy.
- Histological evaluation is crucial for assessing novel grafting materials.
Purpose of the Study:
- To evaluate the histomorphometric performance of an equine-derived bone graft material.
- To assess new bone formation and graft remodeling following sinus floor elevation.
Main Methods:
- Seventeen patients underwent sinus lift surgery using an equine bone graft.
- Bone biopsies were collected six months post-surgery during implant placement.
- Histomorphometry was performed on decalcified bone samples.
Main Results:
- Equine bone graft demonstrated effectiveness in sinus floor elevation.
- New bone formation constituted 40% of the retrieved tissue.
- Residual graft material comprised 33%, and fibrous tissue 27%.
- A reduction in graft particle size indicated remodeling activity.
Conclusions:
- The equine-derived bone graft is effective for inducing new bone formation in sinus floor elevation.
- The material shows promising results for maxillary bone reconstruction.
