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DA+ data acquisition and analysis software at the Swiss Light Source macromolecular crystallography beamlines
Justyna Aleksandra Wojdyla1, Jakub W Kaminski1, Ezequiel Panepucci1
1Swiss Light Source, Paul Scherrer Institute, 5232 Villigen, Switzerland.
Journal of Synchrotron Radiation
|December 23, 2017
Summary
The DA+ data acquisition software enhances macromolecular crystallography (MX) experiments at synchrotron facilities. This Python and Java-based system provides real-time data quality feedback for efficient beamline utilization.
Area of Science:
- Structural Biology
- Crystallography
- Synchrotron Radiation
Background:
- Macromolecular crystallography (MX) relies on efficient data acquisition at synchrotron beamlines.
- Modern MX beamlines require advanced software for optimal performance.
Purpose of the Study:
- To introduce the DA+ data acquisition software developed at the Paul Scherrer Institute.
- To highlight its implementation and capabilities at the Swiss Light Source (SLS) MX beamlines.
Main Methods:
- DA+ software is built using distributed services and components in Python and Java.
- It employs messaging and streaming technologies for inter-component communication.
- Key components include user interface, acquisition engine, online processing, and database.
Main Results:
- DA+ is implemented across all three SLS MX beamlines.
- Distributed automatic data analysis routines provide immediate data quality feedback.
- The software architecture supports advanced instrumentation like SmarGon and EIGER detectors.
Conclusions:
- DA+ software optimizes data collection efficiency at SLS MX beamlines.
- Its architecture facilitates the use of cutting-edge instrumentation and method development.
- This system is crucial for maximizing synchrotron beam time in MX research.