Mesenteric Ischemia

Robin M Lawson1

  • 1Academic Programs, The University of Alabama, Capstone College of Nursing, 650 University Boulevard, East, Tuscaloosa, AL 35401, USA.

Insights

Mesenteric ischemia, a condition of inadequate blood flow to the intestines, can lead to bowel necrosis. Early diagnosis with CT angiography and endovascular therapy are crucial for treating acute mesenteric ischemia (AMI).

Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Radiology

Background:

  • Mesenteric ischemia is a rare condition, primarily affecting the elderly.
  • It stems from insufficient blood flow in the mesenteric circulation, potentially causing bowel necrosis.
  • Mesenteric ischemia is classified into acute (AMI) and chronic (CMI) types, with delayed CMI diagnosis risking progression to AMI.

Purpose of the Study:

  • To summarize the pathophysiology and clinical presentation of mesenteric ischemia.
  • To highlight the diagnostic and therapeutic recommendations for acute mesenteric ischemia.

Main Methods:

  • Literature review of mesenteric ischemia, focusing on diagnosis and treatment.
  • Emphasis on computed tomography angiography (CTA) for early detection.
  • Discussion of endovascular therapy as a primary treatment modality.

Main Results:

  • Acute mesenteric ischemia (AMI) carries a high mortality rate.
  • Delayed diagnosis of chronic mesenteric ischemia (CMI) can precipitate AMI.
  • Computed tomography angiography (CTA) enables early diagnosis.
  • Endovascular therapy offers prompt revascularization.

Conclusions:

  • Early diagnosis of mesenteric ischemia is critical.
  • Computed tomography angiography (CTA) is the recommended diagnostic tool.
  • Endovascular therapy is advised for symptomatic patients without bowel necrosis to prevent mortality.

Related Concept Videos

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...