Related Experiment Video

Updated: Feb 12, 2026

Engineering Skeletal Muscle Tissues from Murine Myoblast Progenitor Cells and Application of Electrical Stimulation
08:38

Engineering Skeletal Muscle Tissues from Murine Myoblast Progenitor Cells and Application of Electrical Stimulation

Published on: March 19, 2013

21.7K

PROSPECTS OF C60 FULLERENE APPLICATION AS A MEAN OF PREVENTION AND CORRECTION OF ISCHEMIC-REPERFUSION INJURY IN THE

S Yu Zay, D A Zavodovskyi, K I Bogutska

    Fiziolohichnyi Zhurnal (Kiev, Ukraine : 1994)
    |March 24, 2018
    PubMed

    Insights

    Accurate diagnostic tests for ischemic injury are lacking. Water-soluble nano-sized C60 fullerenes show promise as antioxidants for treating muscle damage caused by free radicals.

    Area of Science:

    • Biomedical Engineering
    • Materials Science
    • Nanotechnology

    Background:

    • Accurate diagnostic tests for rapid detection of ischemic injury are urgently needed.
    • The destructive effects of free radicals contribute to muscle system damage.
    • Research is ongoing to find specific markers for ischemia and new therapeutic agents.

    Purpose of the Study:

    • To investigate the potential of water-soluble nano-sized C60 fullerenes as therapeutic agents for ischemic injury.
    • To evaluate the antioxidant properties of C60 fullerenes in correcting muscle states affected by free radical damage.

    Main Methods:

    • Utilized water-soluble nano-sized C60 fullerenes.
    • Focused on their antioxidant capabilities.
    • Assessed their effects on muscle system states influenced by free radicals.

    Main Results:

    • Nano-sized C60 fullerenes demonstrated powerful antioxidant properties.
    • These fullerenes show potential for correcting muscle system states affected by ischemia.
    • The study highlights their role in mitigating free radical damage.

    Conclusions:

    • Water-soluble nano-sized C60 fullerenes are promising therapeutic agents for ischemic injury.
    • Their antioxidant capacity can help manage muscle damage.
    • Further research is warranted to explore their clinical applications.

    More Related Videos

    Murine Model of Intestinal Ischemia-reperfusion Injury07:07

    Murine Model of Intestinal Ischemia-reperfusion Injury

    Published on: May 11, 2016

    20.7K
    Laser-inflicted Injury of Zebrafish Embryonic Skeletal Muscle07:13

    Laser-inflicted Injury of Zebrafish Embryonic Skeletal Muscle

    Published on: January 30, 2013

    10.9K

    Related Concept Videos

    Classification of Skeletal Muscle Fibers01:48

    Classification of Skeletal Muscle Fibers

    Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
    Slow-Twitch Muscle Fibers
    Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...
    59.6K
    Overview of Skeletal Muscle01:15

    Overview of Skeletal Muscle

    Skeletal muscles are composed of a bundle of muscle fibers and are attached to bones through tendons. Each skeletal muscle fiber is a single muscle cell. The sarcolemma, the plasma membrane of a skeletal muscle cell, consists of a lipid bilayer and glycocalyx that supports muscle fibers. The sarcolemma extends into the muscle cells to form tubular structures called transverse or T-tubules. Each side of the T-tubules consists of a membrane-bound structure called the sarcoplasmic reticulum,...
    14.8K
    Relaxation of Skeletal Muscles01:29

    Relaxation of Skeletal Muscles

    The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
    When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
    6.0K
    Disorders of the Skeletal Muscle01:28

    Disorders of the Skeletal Muscle

    The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
    Musculoskeletal disorders
    Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
    1.9K
    Naming Skeletal Muscles01:19

    Naming Skeletal Muscles

    The naming of the approximately 700 muscles in the human body is based on a set of criteria designed to provide descriptive information about each muscle, making it easier to identify and remember them.
    The key factors used in naming muscles include:
    4.1K
    Skeletal Muscle Anatomy00:55

    Skeletal Muscle Anatomy

    Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.
    92.9K