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Updated: Feb 11, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
OCT Based Macular Thickness in a Normal Indian Pediatric Population.
Bharti Nigam1, Pragati Garg1, Lubna Ahmad1
1Department of Ophthalmology, Era's Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.
This study establishes normal macular thickness ranges for children aged 5-17 using Cirrus optical coherence tomography (OCT). These findings aid in diagnosing pediatric macular disorders.
Area of Science:
- Ophthalmology
- Medical Imaging
- Pediatric Eye Care
Background:
- Optical coherence tomography (OCT) offers high-resolution retinal imaging.
- Existing OCT normative databases lack pediatric macular thickness data.
- Accurate pediatric macular thickness ranges are crucial for diagnosing eye conditions.
Purpose of the Study:
- To establish the normal reference range for macular thickness in pediatric subjects.
- To provide normative data for children aged 5-17 years.
- To support the diagnosis of macular disorders in pediatric populations.
Main Methods:
- Recruited 170 children (340 eyes) aged 5-17 years.
- Conducted comprehensive ophthalmic examinations.
- Measured macular thickness using Cirrus HD-OCT with dilated pupils.
Main Results:
- Mean macular thickness: 114.88 ± 14.74 μm (right eye), 113.99 ± 15.62 μm (left eye).
- Macular thickness distribution: highest in the inner macula, followed by the outer macula and central fovea.
- No significant difference in macular thickness between right and left eyes (P = 0.589).
Conclusions:
- Normative macular thickness data for pediatric subjects (5-17 years) were determined.
- This data will assist clinicians in diagnosing macular disorders in children.
- Highlights the importance of age-specific normative data in ophthalmology.
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