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Related Experiment Video

Updated: Feb 11, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

Polyester elastomers for soft tissue engineering.

Hongye Ye¹, Kangyi Zhang, Dan Kai

¹Institute of Materials Research and Engineering (IMRE), 2 Fusionopolis Way, #08-03 Innovis, Singapore 138634, Singapore. lohxj@imre.a-star.edu.sg.

Chemical Society Reviews

|May 4, 2018

Summary

This summary is machine-generated.

Biodegradable polyester elastomers offer soft, biocompatible materials for tissue engineering. This review covers their synthesis, fabrication, and biomedical applications, particularly in ophthalmology, cardiac, and vascular tissue regeneration.

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Last Updated: Feb 11, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

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Published on: March 8, 2019

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Published on: February 6, 2016

Area of Science:

Biomaterials Science
Polymer Chemistry
Regenerative Medicine

Background:

Polyester elastomers are soft, biodegradable, and biocompatible, making them ideal for biomedical applications like tissue engineering.
Traditional tissue engineering scaffolds often use biological materials that can trigger adverse immunological responses.
Synthetic polyesters provide an alternative with tunable properties and reduced immunogenicity.

Purpose of the Study:

To review recent advancements in elastomeric polyesters for biomedical applications.
To discuss synthesis and fabrication techniques for these materials.
To highlight their specific uses in ophthalmology, cardiac, and vascular tissue engineering.

Main Methods:

Literature review of elastomeric polyesters in tissue engineering.
Analysis of synthesis and fabrication methods (e.g., solvent casting, 3D printing, electrospinning).
Examination of applications in ophthalmology, cardiac, and vascular regenerative medicine.

Main Results:

Elastomeric polyesters can be fabricated using diverse techniques, offering versatility in scaffold design.
These materials show promise in addressing limitations of biological scaffolds, such as immunogenicity.
Specific applications in eye, heart, and blood vessel tissue engineering are detailed.

Conclusions:

Elastomeric polyesters represent a significant advancement in tissue engineering scaffolds.
Their biocompatibility, biodegradability, and fabrication flexibility enable diverse biomedical applications.
Further development and clinical translation are expected for ophthalmology, cardiac, and vascular regeneration.