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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
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Environmental Panels as a Proxy for Nursing Facility Patients With Methicillin-Resistant Staphylococcus aureus and
Marco Cassone1, Julia Mantey1, Mary Beth Perri2
1Department of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan Medical School, Ann Arbor.
Summary
Environmental screening of high-touch surfaces in nursing facilities can effectively detect methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE), offering a cost-effective surveillance alternative.
Area of Science:
- Infection Control and Hospital Epidemiology
- Microbiology
- Public Health
Background:
- Nursing facilities (NFs) often lack surveillance programs for methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) due to resource limitations.
- High costs associated with traditional surveillance methods present a significant barrier for many NFs.
Purpose of the Study:
- To investigate the effectiveness of environmental screening of high-touch surfaces as a surrogate for patient colonization.
- To develop a cost-effective surveillance strategy for MRSA and VRE in nursing facilities.
Main Methods:
- Compared MRSA and VRE culture data from high-touch surfaces in patient rooms across six NFs.
- Developed MRSA- and VRE-specific environmental panels based on performance in predicting patient colonization.
- Utilized molecular typing to confirm patient-environment isolate relationships.
Main Results:
- Validated MRSA panel: bed controls, nurse call button, bed rail, TV remote. Validated VRE panel: toilet seat, bed controls, bed rail, TV remote, top of side table.
- Environmental panels demonstrated high negative predictive values (MRSA: 89%-92%, VRE: 82%-84%) for patient colonization.
- Molecular typing confirmed strong clonal relationships between patient and environmental isolates (MRSA: 98%, VRE: 91%).
Conclusions:
- Environmental panels can serve as a proxy for patient colonization, aiding in decolonization strategies and transmission reduction.
- Targeted environmental screening is a viable and potentially cost-effective surveillance strategy for MRSA and VRE in NFs.
- This approach can improve awareness of pathogen burden and inform infection control practices in resource-limited settings.
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