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Published on: August 18, 2014
ENERGY PROFILE OF RATS WITH OVERACTIVE BLADDER SYNDROME PHARMACOLOGICALLY CORRECTED WITH QUERCETIN
O Iatsyna1, N Diachkova1, M Kharkhota1
11Odessa National Medical University; 2State Institute "Shalimov National Institute of Surgery and Transplantation" of the National Academy of Medical Sciences of Ukraine; 3D.K. Zabolotny Institute of Microbiology and Virology of the NAS of Ukraine, Kyiv, Ukraine.
Abstract:
We studied the effect of Quercetin on energy profile of erythrocytes of rats with the overactive bladder syndrome. It was shown that animal models with the subject pathology demonstrated alteration of quantitative composition of the adenine nucleotide system in erythrocytes. Abrupt decrease of the total concentration of adenyl nucleotides and ATP compared to the intact group of animals was noted in the study. Administration of Quercetin significantly improved the energy profile of erythrocytes in rats with the overactive bladder syndrome. The data obtained provide new findings of the pathogenesis and correction regimens for the subject pathology.
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