Related Experiment Video
Updated: Feb 7, 2026

A Pleural Effusion Model in Rats by Intratracheal Instillation of Polyacrylate/Nanosilica
Published on: April 12, 2019
Rapid Fire: Pericardial Effusion and Tamponade.
Akilesh P Honasoge1, Sarah B Dubbs2
1Department of Emergency Medicine, University of Maryland Medical Center, 110 South Paca Street, 6th Floor, Suite 200, Baltimore, MD 21201, USA; Department of Internal Medicine, University of Maryland School of Medicine, 110 South Paca Street, 6th Floor, Suite 200, Baltimore, MD 21201, USA.
Malignancy is a common cause of pericardial effusion. Emergency physicians should suspect cardiac tamponade in cancer patients with tachycardia, dyspnea, and hypotension, enabling prompt diagnosis and treatment.
Area of Science:
- Cardiology
- Oncology
- Emergency Medicine
Background:
- Malignancy is a leading cause of pericardial effusion in Western countries.
- Pericardial effusion can lead to cardiac tamponade, a life-threatening condition.
Observation:
- Patients with known or suspected malignancy presenting with tachycardia, dyspnea, and hypotension require high clinical suspicion for pericardial effusion and tamponade.
- Key physical examination findings, electrocardiogram (ECG) changes, and sonographic evidence aid in diagnosis.
Findings:
- Diagnostic findings include specific physical signs, ECG abnormalities, and echocardiographic features suggestive of effusion and tamponade.
- Rapid diagnosis is crucial for effective management.
Implications:
- Prompt recognition and diagnosis of malignant pericardial effusion and tamponade are critical for patient outcomes.
- Emergent pericardiocentesis is indicated for hemodynamically unstable patients to relieve pressure and restore cardiac output.
Related Concept Videos
Behavior of Gas Molecules: Molecular Diffusion, Mean Free Path, and Effusion
Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Rapidly Varying Flow
RACE - Rapid Amplification of cDNA Ends
Plant Tissue Culture

