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Acute Delirium Associated With Levofloxacin
Yana Kogan1, Nizar Elias1, Alona Paz2
1Department of Internal Medicine A, Bnai Zion Medical Center, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Journal of Clinical Medicine Research
|August 18, 2018
Summary
Delirium is a common complication in elderly patients, often unrecognized. This case highlights levofloxacin, a common antibiotic, as a potential cause of drug-induced delirium.
Area of Science:
- Geriatrics
- Pharmacology
- Neurology
Background:
- Delirium is a frequent and serious complication in hospitalized elderly patients, associated with significant morbidity and mortality.
- Drug-induced delirium is a known phenomenon, with sedatives, narcotics, and anticholinergics being common culprits.
Observation:
- Delirium associated with antibiotics is infrequently reported.
- Only seven cases of levofloxacin-induced delirium have been previously documented in medical literature.
Findings:
- This report details an additional case of delirium in an elderly patient treated with levofloxacin for pneumonia.
- This case adds to the limited but growing evidence of levofloxacin as a potential cause of delirium.
Implications:
- Physicians should be more aware of the potential for levofloxacin to cause delirium, an underdiagnosed adverse effect.
- Increased awareness may lead to earlier recognition and management of levofloxacin-induced delirium in elderly patients.
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